chemistry student-faculty research: yu liu, phd
chemistry student-faculty research: yu liu, phd
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my organic chemistry research has two focal points:
- develop novel methodologies for chemoselective benzylic oxidations. these reactions would be valuable tools in the synthesis of structurally complex organic compounds.
- explore new synthetic strategy for the preparation of tetrazines, a class of intriguing heterocyclic compounds that could be used in molecular labeling, fluorescent imaging and site-specific drug delivery.
research students
class of 2018 | class of 2019 | class of 2020 |
---|---|---|
nicolas bader | clayton carroll | vincent galate |
baylie carroll | marcus cronin | |
william houseman | lucas handlin | |
dylan mckee | evan johnson | |
danielle rinck | ||
brendan sweetman |
selected research publications
- “conformationally strained trans-cyclooctene (stco) enables the rapid construction of 18f-pet probes via tetrazine ligation” wang, m.; svatunek, d.; rohlfing, k.; liu, y.; wang, h.; giglio, b.; yuan, h.; wu, z.; li, z.; fox, j. theranostics, 2016, 6 (6), 887-89.
- “recent advances in catalytic selective synthesis of epoxide and aziridine via diazocarbonyl compound” liu, y. curr. org. chem. 2016, 20 (1), 19-28.
- “asymmetric catalytic intramolecular carbon-hydrogen insertion” doyle, m.; liu, y.; ratnikov, m.; bykowski, d. organic reactions. vol 80, john wiley & son, inc., hoboken, nj. 2013.
- “pericyclic reaction of a zwitterionic salt of an enedione-diazo ester. a novel strategy for the synthesis of highly functionalized resorcinols” liu, y.; bakshi, p.; zavalij, p.; doyle, m. org. lett. 2010, 19, 4304.
- “construction of highly functionalized diazoacetoacetates via catalytic mukaiyama-michael reactions” liu, y.; jee, n.; doyle, m. org. lett. 2008, 8, 1605.
recent presentations at academic conferences
- “investigation of chemoselective benzylic oxidation transforming toluene to benzaldehyde” carroll, c.; sweetman, b.; handlin, l.; liu, y. 255th national meeting of the american chemical society, march 18-22, 2018; new orleans, la.
- “effective identification of benzaldehyde product in oxidation reactions involving a co(ii)/tempo catalytic system.” sweetman, b.; handlin, l.; liu y. midwest region meeting of the american chemical society, october 18-20, 2017; lawrence, ks.